As we dive into Week 2 of the 2025 MLB season, fantasy managers face critical decisions regarding player drops and replacements. While knee-jerk reactions can lead to poor choices, evaluating player roles and performance trends is essential. Kirby Yates of the Los Angeles Dodgers is notably struggling, having lost his closer role to Tanner Scott, making him a candidate for drop unless you’re in a deep league. Similarly, David Bednar's demotion after inconsistent performances forces managers to reconsider his roster spot.

Jurickson Profar faces an 80-game suspension for violating MLB's PED policy, and with no IL designation available, he’s nearly unstartable. On the flip side, players like Colton Cowser and Jared Jones have injuries but show potential for returns later in the season, suggesting patience may pay off. As the season progresses, staying alert to these situations will be key for success in fantasy leagues.