As the 2025 MLB season kicks off, several teams are facing unique closing situations that fantasy managers need to monitor. The Baltimore Orioles have yet to secure a save opportunity, primarily due to Félix Bautista's performance, which shows decreased velocity and poor metrics. The Chicago Cubs' Ryan Pressly has the role but his alarming strikeout rate may lead to a change.

Meanwhile, the Chicago White Sox are in a save committee with no standout options. The Cincinnati Reds' Emilio Pagán is up for saves, but with Hunter Greene's potential return, changes could be imminent. The Los Angeles Dodgers have a fluid closing situation with Tanner Scott favored, but the matchup-dependent nature of this role complicates matters. Fantasy managers should keep an eye on the Miami Marlins' Anthony Bender, who is emerging as a reliable option, while the Philadelphia Phillies' Jordan Romano and José Alvarado could shape a competitive endgame.