On this Sunday, April 20, 2025, top MLB DFS picks include standout pitchers and valuable hitters across both DraftKings and FanDuel. Jesus Luzardo, facing the Miami Marlins, shows tremendous strikeout potential with a solid 2.31 ERA and has struck out 29 batters in 23.2 innings. Meanwhile, Tarik Skubal is on a hot streak, with 13 consecutive shutout innings against the Kansas City Royals, making him a prime target. Hitting-wise, the Boston Red Sox's Rafael Devers is now finding his rhythm, while Gunnar Henderson of the Baltimore Orioles is also emerging as a sleeper pick following a recent strong showing.

With matchups at Boston's Fenway Park and Coors Field, where high-scoring games are anticipated, there's potential for explosive performances. Stacking players from these games provides an edge for DFS players. The Boston Red Sox's matchup against Sean Burke and the Philadelphia Phillies against Connor Gillispie are particularly enticing. Look for a combination of Devers, Abreu, and Turner to capitalize on these favorable conditions.

As always, stay updated on injury news and lineup changes, which are critical for optimizing your DFS lineups today.

Tuesday's MLB slate showcases all 30 teams, with a focus on intriguing matchups and aces on the mound. Key pitchers include Zack Wheeler, Dylan Cease, and Chris Sale, but each faces challenges, making Freddy Peralta and Cole Ragans appealing options for DFS players. Hitter havens such as Coors Field are pivotal for fantasy lineups, especially with the Brewers and Rays being strong stacking options.

Among hitters, Jackson Chourio is on a hot streak for the Brewers, while Gunnar Henderson looks to regain form against Merrill Kelly. Pavin Smith remains a viable value pick, and the Reds offer budget-friendly options in Gavin Lux and Santiago Espinal. Stacking the Cubs against Patrick Corbin is also highly recommended due to Corbin's struggles from last season.

Baltimore Orioles All-Star shortstop Gunnar Henderson is set to make his season debut tonight against the Kansas City Royals after being activated from the injured list. Henderson had been recovering from a right intercostal strain that sidelined him for the first seven games of the season. The 23-year-old will lead off and play shortstop in the game.

Last season, Henderson made a significant impact, finishing fourth in American League MVP voting with a .281 batting average, 37 home runs, and 92 RBIs. His recent rehab stint at Triple-A Norfolk saw him hit .263 with two home runs and four RBIs. Despite committing three errors during the rehab games, manager Brandon Hyde expressed optimism about Henderson's readiness, noting that he felt great swinging the bat and just needed game reps.

Gunnar Henderson is set to make his return to the Baltimore Orioles lineup on Friday against the Kansas City Royals after recovering from a right intercostal strain that sidelined him at the start of the season. Manager Brandon Hyde confirmed that Henderson is "probable" for the series opener, as he was not activated for Thursday's game against the Boston Red Sox.

In 2024, Henderson had an impressive season, batting .281 with 37 home runs, 92 RBIs, and 21 stolen bases, finishing fourth in the American League MVP race. Despite his absence, the Orioles have maintained a potent offense, scoring eight or more runs in four of their first six games, although they were shut out by the Red Sox in their last outing.