As Week 5 of the 2025 fantasy baseball season approaches, several catchers are positioned to make an impact on waiver wires. Sean Murphy of the Atlanta Braves stands out, boasting six home runs in his first 14 games this season after returning from injury. His recent performance suggests he could be a reliable starter and a streaming option, particularly with three upcoming games in Coors Field against a struggling Colorado pitching staff.

Francisco Alvarez of the New York Mets is another catcher worth targeting as he returns from injury. His power potential remains intact despite a disappointing 2024 season. With a favorable seven-game schedule against weaker pitching, he could quickly return to form. For deeper leagues, Agustin Ramirez from the Miami Marlins is making waves, hitting .700 with a home run in his first three major league games. Ryan Jeffers of the Minnesota Twins, now gaining more playing time, looks to capitalize on favorable matchups as he transitions to an everyday catcher role. These players represent potential game-changers for fantasy owners seeking to bolster their catching lineup.