With MLB's 2025 season kicking off, it's time to assess the Daily Fantasy Sports (DFS) landscape. Eight games are slated for Friday evening, providing ample opportunity for lineup optimization. Key pitching options include Luis Castillo of the Seattle Mariners, who despite a mediocre ERA last year, thrived in his home ballpark. Jeffrey Springs, newly with the Athletics, is another compelling choice, boasting a remarkable ERA from his previous season. For budget-friendly hitters, Yainer Diaz stands out as a catcher with impressive OPS figures against right-handers, while rookie Griffin Conine offers upside against a struggling Miami lineup.

As for stacking options, consider the Diamondbacks' trio of Corbin Carroll, Ketel Marte, and Josh Naylor against Cubs pitcher Jameson Taillon, whose past performances suggest vulnerability. Similarly, the Pirates’ Oneil Cruz and Bryan Reynolds are solid candidates against the Marlins, especially with Miami's lackluster starting pitching. Overall, a strategic approach based on past performances and current matchups could lead to successful DFS lineups this early in the season.