Wednesday's MLB slate offers a blend of potential and risk as teams gear up for an afternoon getaway schedule, with 10 matchups starting at 6:35 p.m. ET. Pitching options are less than stellar, but Aaron Nola stands out at $9,000 against the strikeout-prone Giants. Brandon Pfaadt and Robbie Ray provide intriguing alternatives, while value options like Clarke Schmidt and Osvaldo Bido may be worth considering.

Offensively, the Rockies' lineup presents a budget-friendly option against struggling pitcher Bobby Miller, while the Red Sox's Jarren Duran and Rafael Devers can be strong plays against Zack Littell. Stacking the Tampa Bay Rays against Sean Newcomb could yield returns, as could rolling with the Dodgers against German Márquez. This is an ideal opportunity for strategists to leverage mismatches and identify underpriced talent.

Today's MLB DFS slate offers a mix of top-tier pitchers and undervalued players to target. Brandon Pfaadt stands out against a struggling Miami lineup, boasting a solid strikeout rate that makes him a must-start in cash games and GPPs. Aaron Nola's matchup with the San Francisco Giants presents a high floor option for consistency, while Kris Bubic's breakout potential against the Yankees adds significant upside for tournament play. Value picks like Rafael Devers and Pavin Smith promise a strong offensive output, especially against pitchers with exploitable splits.

In the outfield, Brent Rooker and Corbin Carroll are poised for big games against favorable matchups. Stacking the Los Angeles Dodgers against German Marquez and the Arizona Diamondbacks against Max Meyer could yield high returns. Weather conditions seem favorable for both games, making it a perfect night for DFS enthusiasts. Stay updated on injury news and starting lineups to maximize your chances for success in today's contests.

As we gear up for the MLB DFS action on April 16, 2025, savvy players will want to explore the recommended lineup picks across both FanDuel and DraftKings. The slate includes 10 games starting at 6:35 PM ET, with a promising mix of elite pitchers and value options.

For pitching, Brandon Pfaadt of the Arizona Diamondbacks stands out with his strong strikeout capabilities, particularly against the Miami Marlins, who struggle against right-handed pitching. Meanwhile, Aaron Nola from the Philadelphia Phillies offers both consistency and a solid matchup against the San Francisco Giants.

Kris Bubic from the Kansas City Royals is a high-risk, high-reward play against a powerful Yankees lineup. Offensively, Rafael Devers is poised to capitalize against the vulnerable Zack Littell, while Pavin Smith and Jose Ramirez represent intriguing infield options. Outfielders such as Brent Rooker and Corbin Carroll also provide considerable upside. The Dodgers, Diamondbacks, and Royals are highlighted as the top stacking options against favorable pitching matchups.

The San Francisco Giants (12-5) are set to face off against the Philadelphia Phillies (10-7) in Game 3 of their four-game series. After a 6-4 loss in Game 2, the Giants will send Robbie Ray to the mound, boasting a record of 3-0 with a 2.94 ERA, to counter Phillies ace Aaron Nola, who is still searching for his first win at 0-3 with a 5.51 ERA. The matchup is critical as both teams seek to gain momentum in this tightly contested series.

The Phillies' recent offensive surge, highlighted by home runs from Bryce Harper and JT Realmuto, indicates a powerful lineup that can capitalize on pitching missteps. For Giants fans, the performance of Justin Verlander, who gave up four runs over 5.2 innings in the last outing, raises questions about the pitching depth. Betting odds reflect a slight edge for the Phillies at -140 on the moneyline with an over/under set at 7.0 runs, suggesting an anticipated competitive game.

On April 16, the Philadelphia Phillies will host the San Francisco Giants at Citizens Bank Park in a pivotal matchup at 6:45 p.m. with Aaron Nola on the mound for the Phillies, seeking his first victory of the season against the undefeated Robbie Ray of the Giants. Fans can catch the action live on NBC Sports Philadelphia (NBCSP), with radio broadcasts available on 94WIP and WDEL. Streaming options include FuboTV, Hulu, Peacock, and MLB.TV.

The Phillies are looking to build momentum in their four-game series against a tough Giants team, and Nola's performance could be crucial for their chances. With both teams having different trajectories early in the season, this matchup will be closely watched by fans and analysts alike.