The 2025 MLB season is heating up, and savvy fantasy managers should keep an eye on two-start pitchers for the upcoming week. Notable options include Jack Flaherty, whose strong 2.63 ERA makes him a must-start against the Astros and Angels. Jacob deGrom is also an intriguing choice, aiming for his first win against the Athletics and Mariners. Keep watch on Cole Ragans, who leads AL strikeouts but requires a health check after a recent groin issue. Newcomer Jack Leiter could shine if he fills in for an injured teammate, facing favorable matchups. Meanwhile, risky options like Miles Mikolas may not be worth the trouble, given his current form.

As the week progresses, fantasy managers should monitor the latest updates, especially for pitchers like Cristopher Sánchez, who is recovering from injury and may have two starts against the Nationals and Diamondbacks. The fantasy baseball landscape is dynamic, so making informed decisions about streaming options can significantly impact standings.