The NBA Wednesday slate features a critical matchup as the New York Knicks aim to secure their first victory against an elite Eastern Conference team this season, facing off against the Cleveland Cavaliers. The Knicks are currently 0-2 against the Cavaliers and 0-3 against the Boston Celtics. Meanwhile, the Cavaliers, who are 4-1 in their last five games, are heavily favored in this matchup. Knicks' OG Anunoby is on a scoring streak, tallying at least 27 points in five consecutive games, with his prop bet set at 21.5 points, offering enticing odds for fantasy bettors.

Player props such as Derrick White for over 0.5 blocks and Ben Simmons for over 0.5 steals are generating interest due to favorable matchups and statistical trends. White's recent performance against the Grizzlies showcased his ability to block shots, while Simmons could benefit from increased minutes against a turnover-prone Pelicans team. Additionally, Alex Sarr's projected points, rebounds, and assists present a valuable opportunity for bettors, alongside Jarrett Allen, who has consistently rebounded this season.