De'Von Achane is poised for a significant performance this weekend, having averaged 11 rushing attempts and at least seven targets per game over his last three outings. He has consistently tallied over 70 all-purpose yards in each game, showcasing elite usage. This week, he faces the San Francisco 49ers, who have allowed the tenth-most PPR points to opposing running backs, presenting Achane with a strong opportunity to excel.

Achane's performance is hindered by a struggling offensive line, which has suffered significant injuries, impacting his rushing efficiency. His yards per carry have declined sharply in recent games, and with potential pressure from the 49ers' defense, he faces a challenging matchup. Additionally, the absence of wide receiver Jaylen Waddle could further limit the Dolphins' offensive capabilities.

De'Von Achane was listed as a full participant in practice, indicating he is likely healthy and ready to contribute as the Dolphins prepare for their upcoming game.

De'Von Achane has struggled to find his footing in the Dolphins' run game, managing only 41 yards on 12 carries in the recent loss to the Texans. This decline comes after a promising start to the season, contributing to Miami's current ranking as the 26th rushing offense in the league.

De'Von Achane, the Dolphins' leading rusher, has seen a decline in his performance this season, averaging only 3.9 yards per carry compared to his impressive 7.8 yards per carry as a rookie. Despite leading the team with 641 rushing yards, his struggles contribute to the Dolphins' overall offensive challenges, particularly in the run game, which has averaged just 58 yards per game over the past six outings.