Cale Makar, a key defenseman for the Colorado Avalanche, will miss the highly anticipated 4 Nations Face-Off game between Canada and the United States due to illness. This marks a significant absence for the Canadian team, which is already without Alex Pietrangelo due to injury and Shea Theodore, who was hurt during a previous match. In Makar's place, Thomas Harley of the Dallas Stars will step into the lineup. The Canadians face a challenge as they navigate through these defensive setbacks in a critical match.