With spring training in full swing, Major League Baseball's 2025 season is on the horizon, prompting teams to finalize their Opening Day starters. This year's line-up is expected to feature some familiar and new faces as teams evaluate their rosters ahead of the season's commencement. Many franchises are looking at changes due to injuries or trades, with notable pitchers like Corbin Burnes, Tarik Skubal, and Yusei Kikuchi highlighted for their likely starting roles. Each team’s Opening Day starter carries significance for fantasy leagues, as these pitchers could set the tone for their seasons.

For instance, the Arizona Diamondbacks may lean towards Corbin Burnes, reflecting a critical offseason acquisition for the team. The Atlanta Braves will likely hand the ball to Chris Sale, aiming to replicate his prior success. In contrast, the Chicago Cubs will see Shota Imanaga making his debut Opening Day start in Japan. Meanwhile, the New York Yankees seem poised to feature Gerrit Cole, while the Philadelphia Phillies will again trust Zack Wheeler, who’s coming off a stellar previous year. As teams make their announcements, tracking these decisions can offer crucial insights for fantasy leagues and betting markets.