Every MLB season brings a fresh wave of fantasy baseball prospects eager to make their mark. With evolving league rules favoring early call-ups, it’s crucial for fantasy players to stay ahead of the curve. Insights into the projected ETAs for notable prospects, categorized from Opening Day to late-season call-ups, provide a roadmap for savvy drafting and in-season strategies.

For 2025, key prospects like Tyler Black (MIL), Ryan Bliss (SEA), Jasson Domínguez (NYY), and Kumar Rocker (TEX) are expected to debut on Opening Day, while others like Luisangel Acuña (NYM) and Kristian Campbell (BOS) may arrive in early season. Mid-season talents include Kevin Alcantara (CHC) and Cade Cavalli (WAS), with late-season prospects such as Samuel Basallo (BAL) and Travis Bazzana (CLE) lined up for potential late-year boosts. This cheat sheet serves as a vital asset for managing rosters and maximizing fantasy points.