On April 16, the Cubs (12-8) face off against the Padres (14-4) in the final game of their series at Petco Park. After a close 2-1 victory in last night's game, Cubs pitcher Matthew Boyd, who boasts a 1.59 ERA, will take the mound against Padres' Nick Pivetta, also with a 1.59 ERA. Boyd's last outing saw him allowing three earned runs over six innings, while Pivetta delivered a stellar performance, throwing seven scoreless innings against Colorado.

The game’s betting odds reflect the tight competition, with the Cubs at +101 and the Padres at -121. Betting insights reveal the Padres' strong performance on the run line at 13-5, with the Cubs leaning towards the over at 13-6-1 this season. Key players to watch include Fernando Tatis Jr., who is on a five-game hitting streak, and Kyle Tucker, hitting .313. Bettors are advised to consider the over on the total runs set at 7.0, with projections favoring the Padres on the moneyline.