As the 2025 MLB season progresses, the fantasy baseball landscape is starting to reveal trends that could reshape team strategies. Dennis Santana, Jonathan India, and Clay Holmes are critical subjects for fantasy managers navigating their rosters. Santana, currently serving as a relief pitcher for the Pittsburgh Pirates, has emerged as a potential closing option. However, his shaky statistics raise concerns about his reliability. India, now with the Kansas City Royals, has a solid foundation in plate discipline, making him an intriguing asset, especially in OBP formats. His ability to contribute across multiple positions adds to his value. Meanwhile, Clay Holmes's recent transition to a starting role with the New York Mets has not been as promising as hoped, suggesting he may not be a viable fantasy option.