As Week 2 of the 2025 fantasy baseball season approaches, it's time to assess waiver wire opportunities for infielders. Rhys Hoskins, currently with the Milwaukee Brewers, offers a promising option with a favorable schedule featuring hitter-friendly venues like Coors Field. Meanwhile, Jake Cronenworth of the San Diego Padres, despite a slow start, could capitalize on a strong team batting average and favorable matchups.

For deeper leagues, Trevor Story of the Boston Red Sox has shown potential with a solid start, while Enrique Hernandez, serving as a versatile option in the Dodgers lineup, could break out. In the deepest leagues, keep an eye on Carlos Santana, who’s been locked in the cleanup spot for the Guardians, and Geraldo Perdomo from the Diamondbacks, who is off to a hot start with an opportunity for more playing time.