The Portland Trail Blazers face a significant challenge against the Minnesota Timberwolves, as they will be missing four players, including starters Anfernee Simons and Deandre Ayton. Simons is sidelined due to an illness that caused him to experience shortness of breath during a previous game, while Ayton is out with a finger injury.

Additionally, center Robert Williams III will also miss the game for rest, despite recently showing improved performance. Matisse Thybulle remains unavailable, further depleting the Trail Blazers' roster.