With the 2025 MLB season heating up, fantasy baseball managers have their eyes set on the upcoming week’s two-start pitchers, a crucial aspect to gaining an edge in leagues. Names like Tarik Skubal, the reigning AL Cy Young winner, return to the mound, and he's expected to shine against the Brewers and Royals. Other notable mentions include Framber Valdez of the Astros, boasting a solid 2.50 ERA, and the Yankees' Max Fried, who has impressed with his early performance.

On the flip side, there are pitchers like Tanner Houck and Carlos Carrasco, whose recent struggles raise doubts about their effectiveness despite matchups that could work in their favor. Fantasy managers will need to weigh the risks associated with their limited track records against the potential upside in favorable situations. Additionally, emerging arms like Jesus Luzardo and Paul Skenes are making waves, with Luzardo potentially being the top overall option this week. Understanding these dynamics will be essential for managers looking to maximize their pitching rotation in the crucial weeks ahead.