The New York Yankees, despite showcasing their power with three home runs, suffered their first loss of the 2025 season against the Arizona Diamondbacks, falling 7-5. The game turned in the eighth inning when a grand slam from Eugenio Suárez overturned the Yankees' lead. Closer Devin Williams was unavailable, forcing a change in the bullpen strategy that contributed to the loss.

Will Warren made a promising debut as the Yankees' starting pitcher, leaving with a 4-2 lead after five innings. The offense remained potent, led by Jasson Domínguez's home run and Anthony Volpe's equalizer. However, the Yankees' lineup, despite powerful performances, struggled against Corbin Burnes, managing only eight strikeouts against him in a disappointing performance.