The San Francisco 49ers suffered another disappointing loss, this time to the Arizona Cardinals, falling 24-23 after leading 23-13 in the fourth quarter. Quarterback Brock Purdy's two second-half interceptions and Jordan Mason's fumble were pivotal in the defeat.

Despite a strong start, including a touchdown from a blocked field goal return, the 49ers were unable to finish drives and protect their lead. This loss marks the sixth time under coach Kyle Shanahan that they have squandered a double-digit lead.