The Los Angeles Chargers are set to face the Arizona Cardinals in a Monday night matchup, with the Chargers favored by three points. Historically, the Chargers lead the series 11-4 and have won five of the last six meetings.
The Chargers are coming off a victory against the Denver Broncos, while the Cardinals suffered a defeat to the Green Bay Packers. Key players to watch include Chargers running back J.K. Dobbins and Cardinals tight end Trey McBride.
Quarterback Kyler Murray will be crucial for the Cardinals as he faces a formidable Chargers defense that allows the fewest points per game in the league. Both teams are dealing with injuries, impacting their lineups.