The Arizona Cardinals faced a disappointing 36-30 overtime loss to the Carolina Panthers, resulting in their elimination from playoff contention. Despite scoring 30 points, the offense struggled significantly after running back James Conner's injury, with quarterback Kyler Murray's performance faltering in critical moments.

Defensively, the Cardinals allowed 380 total yards and failed to contain the Panthers' rushing attack, which gained 243 yards. The team's undisciplined play led to 11 penalties, further compounding their issues on the field.