The Buffalo Bills face the Arizona Cardinals on September 8 with significant injury concerns, as rookie defensive end Javon Solomon is ruled out due to an oblique issue.

Sean McDermott confirmed that fellow defensive end Dawuane Smoot is questionable with a toe injury. The team has several players cleared to play, including safety Cole Bishop and quarterback Mitch Trubisky.

Arizona will miss wide receiver Xavier Weaver, while safety Joey Blount and tight end Tip Reiman are both questionable for the matchup.