The Arizona Cardinals are poised for a significant challenge in their week three matchup against the Detroit Lions, hoping to secure their first winning record since 2021. After starting the season with a competitive 1-1 record against playoff teams, they aim to outsmart a strong Lions team that has set a benchmark for rebuilding.

To succeed, the Cardinals must implement strategies to mitigate the impact of star defensive player Aidan Hutchinson, who poses a considerable threat to quarterback Kyler Murray. Despite some injuries hampering their offensive line, inventive protection schemes will be essential to keep Murray upright and effective.

Defensively, the Cardinals must apply pressure on Jared Goff and contain the Lion's running game, which features David Montgomery and Jahmyr Gibbs. They must also utilize their offensive weapons wisely to create mismatches that exploit Detroit's secondary. Ensuring efficient ball distribution from Murray could be key to achieving a balanced and dynamic offense against a fundamentally sound Lions defense.