Drew Lock is set to start as quarterback for the New York Giants against the Indianapolis Colts, aiming to break a franchise-record 10-game losing streak. After a rough outing against the Atlanta Falcons, where Lock struggled with turnovers, he has received medical clearance for his shoulder injury.

Coach Brian Daboll emphasized the importance of giving Lock consistent practice reps. The Giants, currently the lowest-scoring team in the NFL, have seen a significant shift in their quarterback lineup following the release of Daniel Jones.