The Buffalo Bills announced their inactive players for Week 3's matchup against the Jacksonville Jaguars, highlighting the absence of key defensive players due to injuries. Rookie Joe Andreessen is notably active, having earned his place on the 53-man roster after a successful training camp.

For Andreessen, this game represents a significant milestone as he prepares to make his NFL debut close to his hometown. This story of determination and opportunity sets the stage for a thrilling primetime debut.