The San Francisco 49ers dominated the Chicago Bears 38-13 in a game marked by Chicago's struggles following the firing of head coach Matt Eberflus. Despite missing key players, the 49ers showcased their offensive prowess, with quarterback Brock Purdy throwing for 325 yards and tight end George Kittle amassing 151 yards.

Meanwhile, the Bears suffered their seventh consecutive loss, struggling offensively and defensively under interim coach Thomas Brown. Their performance raised concerns about their playoff hopes as they fell to 4-8.