The impact of Patrick Mahomes' ankle injury on the betting odds for the upcoming Houston Texans-Kansas City Chiefs game highlights his importance to the team. Initially, the Chiefs were favored by five points, but the spread shifted to favor the Texans after Mahomes' injury during a game against the Cleveland Browns.

However, following Mahomes' participation in practice, the odds reverted to favor the Chiefs. Teammate Travis Kelce expressed confidence in Mahomes' ability to play, emphasizing his toughness and commitment to the team's success.