The NFL's 'next man up' approach extends to fantasy football, requiring managers to adapt as the season progresses.

This week, attention turns to players like Puka Nacua of the Los Angeles Rams, sidelined due to a knee injury, impacting many fantasy rosters.

Players stepping in, such as Tyler Johnson and Demarcus Robinson, are recommended for stashing as they face favorable matchups.

Additionally, Rashid Shaheed, Brandin Cooks, and Wan'Dale Robinson rise in prominence, offering potential contributions despite their teams' challenges.

Quarterbacks Baker Mayfield and Matthew Stafford present strong options in the wake of injuries to others, while running backs like Bucky Irving and Alexander Mattison show readiness to step up.