In a dominant performance, Josh Jacobs rushed for 106 yards and three touchdowns, leading the Green Bay Packers to a 38-10 victory over the San Francisco 49ers. This marked the first time in 55 games that an opponent rushed for over 100 yards against the 49ers, who were missing key players due to injuries.

Quarterback Brandon Allen struggled in his first start since 2021, while Packers' Jordan Love threw for 163 yards and two touchdowns. The Packers scored on their first three possessions, establishing an early lead that the 49ers could not overcome.