As Week 5 approaches, injuries are impacting several key NFL players, affecting fantasy football decisions. Joe Mixon and Dameon Pierce are sidelined, while Malik Nabers is unlikely to play due to a concussion. T.J. Hockenson is returning to practice, but his game status remains uncertain.

Davante Adams is week-to-week with a hamstring injury and may not play against the Denver Broncos. Trey McBride is expected to return from concussion protocol, while George Kittle's rib injury keeps him day-to-day. Other notable injuries include Brian Robinson Jr., Travis Etienne Jr., Zamir White, Evan Engram, Devin Singletary, and Odell Beckham Jr.