The AFC South has showcased a competitive landscape as the season reaches its midpoint. The Jacksonville Jaguars and Indianapolis Colts lead with eight selections among the best players in their division.

Trevor Lawrence stands out as the top quarterback, while Tony Pollard is recognized as the leading running back. Wide receivers Nico Collins, Josh Downs, and Brian Thomas Jr. also make the cut, alongside standout tight end Evan Engram.

On the defensive side, Josh Hines-Allen and Danielle Hunter are noted as top edge defenders, with Grover Stewart and Jeffery Simmons leading the interior. The Colts' Kenny Moore II and Samuel Womack III shine in the cornerback category, while Quandre Diggs and Julian Blackmon are recognized as the top safeties.