Alec Pierce, a key player for the Indianapolis Colts, is sidelined due to a concussion ahead of their matchup with the Denver Broncos. This absence shifts the focus to other receivers like Michael Pittman Jr., Josh Downs, and AD Mitchell, while the Colts continue to lean on their ground game led by Anthony Richardson and Jonathan Taylor.

The Broncos, dealing with turnover issues from rookie quarterback Bo Nix, may provide the Colts with opportunities to capitalize on their offensive strategy, primarily relying on their strong offensive line.