The Jacksonville Jaguars have issued their injury report ahead of their Week 18 matchup against the Indianapolis Colts. Offensive tackle Walker Little is expected to miss the remainder of the 2024 season due to an ankle injury sustained in Week 16, rendering him a non-participant in practice. Coach Doug Pederson confirmed Little's condition, noting he was seen in a walking boot.

In response to Little's absence, the Jaguars have appointed veteran offensive lineman Cole Van Lanen as the starting left tackle. Van Lanen, who played every snap in the previous game, received praise from quarterback Mac Jones, who highlighted their strong friendship and Van Lanen's hard work. Additionally, the injury report includes limited participants such as Ezra Cleveland, Brandon Scherff, Darnell Savage, and Ventrell Miller, with Scherff's shoulder injury being a concern after he briefly left the last game.