Tennessee Titans running back Julius Chestnut will not participate in the upcoming game due to injury, limiting his fantasy relevance. Meanwhile, Tony Pollard and Tyjae Spears are set to lead the backfield, with Pollard taking the primary role and Spears providing support.

Other notable players include Los Angeles Chargers' Joshua Palmer, who, despite recent performances, remains a sit option due to low target share. San Francisco 49ers' Isaac Guerendo is also expected to see limited action behind Christian McCaffrey.