This article provides fantasy football insights for Week 4, featuring key players to start or sit based on their matchups.

Pittsburgh Steelers' George Pickens is highlighted as a potential strong play due to the Indianapolis Colts' defensive struggles against wide receivers.

Other notable players discussed include Tyreek Hill, Chuba Hubbard, Zack Moss, Brian Robinson Jr., and Josh Jacobs, each with varying degrees of recommended fantasy value.