The Indianapolis Colts faced a disappointing defeat against the Minnesota Vikings, losing 21-13 despite Joe Flacco's efforts to replace Anthony Richardson. Flacco's performance was marked by 179 passing yards, no touchdowns, and one interception, highlighting the offense's struggles without Richardson's versatility.

On the other hand, Sam Darnold led the Vikings with a solid outing, completing 28 of 34 passes for 290 yards and three touchdowns. Justin Jefferson was a standout performer, contributing significantly with seven catches for 137 yards and a passing touchdown.