In a highly emotional matchup, Sean Payton returns to New Orleans as the Denver Broncos face the Saints, both teams reeling from Week 6 losses. The game highlights key injuries for the Saints, including Derek Carr and Chris Olave, while the Broncos look to capitalize on their defensive resurgence led by Zach Allen.

Meanwhile, the Kansas City Chiefs and San Francisco 49ers meet in a Super Bowl rematch, with both teams aiming to solidify their standings early in the season. Other notable games include the New England Patriots against the Jacksonville Jaguars and the Tennessee Titans facing the Buffalo Bills, as teams navigate injuries and trades impacting their rosters.