Quinyon Mitchell showcased impressive poise in his debut as a cornerback for the Philadelphia Eagles, becoming the first rookie to start for the franchise in Week 1 since 1988. Despite being heavily targeted by the Green Bay Packers, he allowed only five completions for 86 yards and recorded two pass breakups.

Head coach Nick Sirianni praised Mitchell's confidence and ability to handle pressure, noting that he faced more targets than his veteran teammate Darius Slay. Mitchell's training camp performances against star receivers A.J. Brown and DeVonta Smith set high expectations for his regular season performance, which he met with calm determination.