The San Francisco 49ers RB2 position in 2024 is up for grabs, with Elijah Mitchell and Isaac Guerendo competing for the job. Mitchell made a splash in 2021, but injuries have hindered his fantasy impact. Guerendo, a fourth-round draft pick known for his elite athleticism, could emerge as a fantasy sleeper this season.

While Mitchell has experience, Guerendo's upside in the event of a Christian McCaffrey injury makes him a valuable stash. Both players offer fantasy potential, but Guerendo's physical prowess and draft status give him an edge in the competition for the RB2 role.