The San Francisco 49ers are looking to build on their recent victory over the New England Patriots as they prepare to face the Arizona Cardinals, who are struggling after two losses. With Brock Purdy at the helm, the Niners aim to exploit the Cardinals' weak pass defense, which ranks near the bottom of the league.
Purdy's performance will be crucial, particularly his sideline passing, which has seen a dip this season. Meanwhile, running back Jordan Mason could shine against a mediocre run defense, and wide receiver Brandon Aiyuk is expected to make a significant impact.
On defense, the 49ers must contain Cardinals quarterback Kyler Murray, who has shown impressive stats this season. The Niners' struggles on third down could be a vulnerability, especially with the potential absence of key defensive player Fred Warner. Tight end Tre McBride presents another challenge, as he returns from injury and has a strong rapport with Murray.