The San Francisco 49ers' season has taken a severe downturn, with injuries crippling their roster and a current record of 5-7. Following a heavy loss to the Buffalo Bills, the team faces a daunting challenge to make the playoffs, trailing the NFC West-leading Seahawks by two games.

Key players such as Christian McCaffrey, Jordan Mason, and Kevin Givens are headed for injured reserve, adding to a long list of injured stars. The team has also faced personal tragedies, further complicating their efforts this season.