Brock Purdy, the San Francisco 49ers quarterback, will not play against the Green Bay Packers due to a sore throwing shoulder, following an injury sustained in the previous game against the Seattle Seahawks.

Coach Kyle Shanahan confirmed that defensive end Nick Bosa is also out with injuries, while left tackle Trent Williams is questionable. This marks Purdy's first missed start since becoming the 49ers' quarterback in December 2022, with Brandon Allen set to take over.