The San Francisco 49ers are looking to bounce back against the New England Patriots after a rough start to the season, having lost their last two games. Quarterback Brock Purdy emphasizes the importance of every play as the team aims to regain its winning momentum.

Key players to watch include linebacker De’Vondre Campbell, who has struggled in pass coverage, running back Jordan Mason, who has stepped up in Christian McCaffrey's absence, and safety Talanoa Hufanga, returning from injury. Wide receiver Brandon Aiyuk needs to improve his performance, while defensive end Nick Bosa must capitalize on the Patriots' left tackle situation.