The San Francisco 49ers are facing significant injury challenges as quarterback Brock Purdy has been added to the list with shoulder soreness following their recent loss to the Seattle Seahawks. Coach Kyle Shanahan indicated that Purdy's condition is day-to-day, and while it doesn't seem long-term, he will be monitored closely during practice.

Defensive end Nick Bosa's status is also uncertain after aggravating a hip injury. Other key players, including tight end George Kittle and left tackle Trent Williams, are being watched for their recovery as the team prepares for their upcoming game against the Green Bay Packers.