In Week 3, several NFL running backs made notable contributions, with varying degrees of success. James Conner remained a focal point for the Arizona Cardinals, despite a lackluster yardage performance. Bijan Robinson of the Atlanta Falcons continued to dominate, while Derrick Henry of the Baltimore Ravens excelled with two touchdowns. The Detroit Lions utilized a split backfield with David Montgomery showcasing better performance than Jahmyr Gibbs.

The Indianapolis Colts' Jonathan Taylor consistently led his team's backfield, whereas Breece Hall of the New York Jets also had a significant presence, outperforming his competition. Injuries and rotations have affected many teams, such as the Miami Dolphins, who struggled amidst quarterback changes. Key questions loom about the fantasy values of several players as we head into Week 4.