In a commanding performance, the Arizona Cardinals overwhelmed the Los Angeles Rams with a 41-10 victory. Kyler Murray shone with 266 passing yards and three touchdowns, showcasing a potent connection with rookie Marvin Harrison Jr., who recorded his first two NFL touchdowns.

The Cardinals led comfortably, 24-3, at halftime and extended their lead in the second half. James Conner's powerful running contributed significantly to the win, as he surpassed 5,000 career rushing yards.

Meanwhile, the Rams struggled on offense, with Matthew Stafford unable to find successful connections and star receiver Cooper Kupp leaving with an ankle injury.