The Buffalo Bills will miss rookie wide receiver Keon Coleman for their Week 13 matchup against the San Francisco 49ers due to a wrist injury. Coleman has been sidelined for three consecutive games after suffering the injury in Week 9.

Despite returning to limited practice, he was ultimately ruled out. The Bills will rely on other pass-catchers, including Amari Cooper and Khalil Shakir, as they prepare for a snowy game in Orchard Park.