The Buffalo Bills, boasting a 10-2 record and riding a seven-game winning streak, head to Los Angeles to face the Rams. After recent victories over the Chiefs and 49ers, the Bills may encounter a potential letdown on the road. Meanwhile, the Rams, at 6-6, are gaining momentum in the NFC West with key players returning, including Puka Nacua and Cooper Kupp, while Matthew Stafford excels with eight touchdowns in his last three games.

As the teams prepare for their matchup, the Bills are favored by 3.5 points, with Josh Allen's interception odds drawing attention. Injury updates reveal key players sidelined for both teams, adding intrigue to this pivotal game at SoFi Stadium.