The Detroit Lions faced a tough defeat against the Buffalo Bills, ending their impressive 11-game winning streak with a 48-42 loss. Head coach Dan Campbell expressed regret over his decision to call for an onside kick in the fourth quarter, a move that ultimately backfired.

Despite the Lions scoring twice after the onside kick, the Bills maintained control, securing the win and marking the Lions' first loss since Week 2. Campbell took full responsibility for the team's performance, acknowledging that they were not prepared for the intensity of the game.