In a decisive victory, the Denver Broncos defeated the New Orleans Saints 33-10, marking coach Sean Payton's return to New Orleans. Javonte Williams scored two touchdowns, while Bo Nix contributed with both passing and rushing yards.

The Saints struggled without key players, including quarterback Derek Carr and top receivers Chris Olave and Rashid Shaheed. Rookie Spencer Rattler was overwhelmed by the Broncos' strong defense, leading to a disappointing fifth consecutive loss for New Orleans.

Halftime honored former QB Drew Brees for his Hall of Fame induction, but the game saw numerous injuries, further complicating the Saints' season.